The dynamic relationship between cytotoxic effect and incubated time with TPT was investigated by flow cytometry and immunological analysis.

• 应用新的流体细胞测量仪(FACS-Vantage)及免疫分析法对细胞培养时间、TPT的浓度与拓扑酶中毒程度的动力学关系进行了研究。