The disruption of glutamic acid strain by a high pressure homogenier,enzyme and autolysis was investigated for the release of intracellutar nucleic acid.

• 采用均质破碎法、加酶法和自溶法等方法对谷氨酸菌进行破碎试验，以使核酸释放，并对相应的工艺参数及检测方法进行了优化研究。