The decreased axospinous synapses and the increased proportion of the perforated axospinous in hippocampal CA1 of aged mice are probably morphological basis in the aged-associated learning and memory impairments.

• 老年小鼠海马CA1区锥体细胞树突棘的减少、穿孔型突触比率的增加可能是衰老引起学习记忆减退的形态学基础。