The crossinking behavior of collagen fibril under UV-B exposure can be clearly observed by means of AFM.It is proved that AFM is an excellent technique for the study of collagen fibril.

• AFM作为一种高分辨的表面分析仪器；为分子生物学领域的研究提供了一种新的手段.；是探讨胶原光作用机理直观、有效的方法