The control animals had no significant changes. Conclusion Subctaneous injection of gentamicin (400mg/kg/day) for 2 days could successfully establish the animal model of toxic acute tubular necrosis.

• 结论 每日皮下注射庆大霉素400mg/kg ，连续2d，可以成功建立中毒性急性肾小管坏死的动物模型。