The conservation in sequence and structure of protein tyrosine phosphatases has been analyzed by aligning their sequences and superposed their three dimensional topological structures.

• 以蛋白质酪氨酸磷酸酶为模型，通过序列和结构的比较，对蛋白质序列、结构的保守性与其功能和进化的关系问题进行了研究。