The concentrations of captopril in plasma samples at different time points were determined by LC/MS/MS and the plasma concentrations-time profiles were obtained.

• 采用液相色谱-质谱-质谱联用法(LC/MS/MS)，分别测定了给药后不同时刻健康受试者血浆中卡托普利的浓度，绘制了血药浓度-时间曲线。