The combination of 5-fluorouracil(5FU) with p14ARF gene could increase the inhibitory function of 5FU and sensitize human colon cancer LOVO cell line to 5FU.

• pl4ARF基因和化疗药物5FU联合用于结肠癌LOVO细胞能够加强5FU的生长抑制作用，明显提高LOVO细胞对5FU的敏感性。