The chimeric oncogene BCR/ABL and Ph chromosome,two hall marks of CML,were detected in CML derived MSCs,normal adult MSCs,CML derived hematopoietic cells and K562 cells.

• RT-PCR检测CML特异性表达的BCR/ABL基因; 对正常人、CML患者的骨髓间质干细胞进行染色体分析。