The central nervous system regulates the peripheral immune cells via acetylcholine-mediated efferent signals carried through the vagus nerve in response to an immune challenge.

• 机体在遭受免疫刺激时，中枢通过传出迷走神经及其递质乙酰胆碱，将免疫调节信息传递给外周免疫细胞，抑制促炎因子释放，保护机体免受伤害。