The cell double time were 72.6 h in C group, 73.5 h in P group, and 98.9 h in MPG group. Cell cycle blockage and subdiploid peak were found in MPG group.

• MPG组细胞增殖能力明显下降；P组及C组细胞增殖能力无明显差异；倍增时间分别为72.；6h(C组)、73