The article introduces the study advance of the gene therapy and the clinical practical concerns of the gene therapy from the three aspects of gene therapies of solo gene disease, tumour and AIDS.

• 从单基因疾病的基因治疗、肿瘤的基因治疗和AIDS疾病的基因治疗三个方面介绍基因治疗的研究进展及基因治疗在临床上的应用概况。