The apoptosis of IH cells may be resulted from the immune response which is caused mainly by T cells and dendritic cells . aiming at the Fas antigen of IH cells and mediated byFas/FasL.

• T细胞和树突状细胞为主的、针对IH细胞的Fas抗原并通过Fas/FasL通路介导的免疫应答可能是IH细胞凋亡的主要原因。