The animal models of rabbits with syndrome of decoction da cheng qi were made by feeding up with bismuth subcarbonate,having no water,and counteracting toxic substances with Bacillus coli endotoxin.

• 结果:采用次碳酸铋、禁水加大肠杆菌内毒素联合造模的方法所研制的家兔病理模型,在症状、体征及微观变化上基本符合临床大承气汤证的特点。