The adhesive forces of GEC-PMN increased after anoxia/oxidative stress, with increasing expression of P-selectin, E-selectin, ICAM-1. The increased adhesive forces were inhibited by the use of ICAM-1 antibody.

• 表明多种粘附分子参与缺氧、氧损伤后TEC的粘附性改变，ICAM1是在介导PMN一内皮牢固粘附中起主要作用的粘附分子。