The activity of bone morphogenetic protein has been confirmation by many experiments, but the clinical apply effect of BMP was not satisfaction till now.

• 骨形态发生蛋白(BMP)的异位诱导成骨活性已被多次实验所证实，但到目前为止，BMP的临床应用效果仍不理想，缺少理想的载体系统是影响BMP诱导成骨效果的主要原因。