The abnormality of TRP channels can lead to some renal diseases such as familial FSGS,ADPKD,and HSH.Further researches on TRP channels would benefit the therapy and preclude of renal disease.

• TRP通道异常可导致遗传性局灶节段硬化性肾病(FSGS),常染色体显性遗传多囊肾(ADPKD),低镁血症继发低钙血症(HSH)等,对TRP通道的进一步研究将有助于临床肾脏病的防治。