The IL 6 IL 6 receptor system in blood is up regulated in active LN patients. Up regulation of the gp80 and gp130 mRNA levels in vivo may be caused by endogeneously PBMC derived IL 6.

• 活动期LN患者PBMCs内IL 6及其受体gp80和 gp130的mRNA表达均上调 ,且受体 g