The DSH locus has recently been mapped to chromosome Iq11-q21 and pathogenic mutations were identified in ADAR, the gene encoding double-stranded RNA-specific adenosine deaminase, in Japanese patients with DSH.

• 日晒后皮损加重，一般无自觉症状。 国内张学军等首先将DSH致病基因定位于染色体1q11-q21，日本学者新近证明DSH是由该区ADAR基因突变所致。