The DCC and mixed anhydride methods were applied to synthesizing theprecursor of RGD and protected tri-peptide, respectively. All protected groups used inRGD synthesis were finally de-protected, and the crude de-protected RGD productwas obtained.

• 本文以DCC法、混合酸酐法分别合成了RGD三肽前体二肽和全保护三肽,最后脱去保护基得到RGD。