The CD spectra of L-aspa-raginase and PEG2-L-asparaginase under different conditions proved that Asn and Gln have serious effect on the conformation of native enzyme but very slight effect on the conformation of modified enzyme.

• 天冬酰胺酶和PEG_2-天冬酰胺酶的CD光谱表明:天冬酰胺和谷氨酰胺对天冬酰胺酶和PEG_2-天冬酰胺酶的构象影响较大,但天冬酰胺酶和PEG_2-天冬酰胺酶的构象变化趋势有明显的不同。