The Ames test was negative. The drugs did not damage chromosome of peripheral lymphocyte of human being ,and did not increase the chromosome distortion ratio of DHL cell and the PCE micronucleus ratio of mice marrow cell.

• Aems试验结果为阴性 ,对人体外周淋巴细胞染色体无损伤 ,对CHL细胞染色体及小鼠骨髓PCE微核率无增加作用。