The 5 - HIAA of APP 751 trangenic mice showed significant difference compared with control group. The DA and 5 - HT of APP695 transgenic mice raised 38.9% and 45.8% respectively compared with control group.

• APP695转基因鼠大脑皮层中DA和5-HT平均含量分别比对照鼠升高38.；9%25和45