Tab 1. Effects of DCDDP on the numbers and relative contents of positive cell of 5-HT and 5-HT receptor in pulmonary tissue of pulmonary hypertensive rats induced by monocrotaline(MCT) .

• 在MCT性肺动脉高压时；大鼠肺组织中5-HT相对含量及其受体阳性细胞数目均显著增高.；DCDDP能够明显地减少MCT引起的5-HT含量及其受体阳性细胞数目增加，中小剂量对5-HT相对含量的影响最为明显，大剂量对5-HT受体相对含量的影响最为明显(表1