Synthetic Oligodeoxynucleotides (ODN) containing CpG motif were demonstrated to mimic a danger signal of bacterial or viral DNA and induce a potent Th1 biased immune response. Therefore, CpG ODN may have potential as a new adjuvant.

• 实验证明，人工合成的含CpG基序的寡脱氧核苷酸(CpG ODN)可以模拟细菌、病毒的自然危险信号，诱发机体产生强烈的Th1型免疫应答，有望成为一类新型的免疫佐剂。