Synthesis of vanillin from guaiacol and glyoxylic acid was studied.The reaction conditions were optimized.The total yield of vanillin was 65.6%.

• 对愈创木酚和乙醛酸缩合一氧化制备香兰素工艺进行了研究；对反应条件进行了优化；使香兰素总收率达65.；6%25。