Structural modification is still popular and important in the area of finding novel quinolone antibacterial agents with more potential activity and broad spectrum.

• 对喹诺酮类化合物进行进一步的结构修饰,以便获得活性更强,活性谱更广的新喹诺酮类抗菌药,仍是抗感染化疗领域近几年的热点领域之一。