So the DNA methylation patterns of mouse tetraploid embryos are aberrant, which may lead to subsequent de-velopmental failure and embryo death.

• 因此, 小鼠体外培养四倍体胚胎的甲基化模式是不正常的, 这可能是四倍体小鼠难以发育到妊娠足月的原因之一。