Small incisions were made in the soft tissue of the upper jaw of the host mice, in a region known as the diastema between the molars and incisors where normally there are no teeth.

• 他们在小鼠上颌臼齿与门齿的牙间隙（此处通常没有牙齿）部位，将软组织切开一个小开口，放入胚胎牙齿原基，再以手术胶密封起来。