Since constitutive expression system is more likely leading to the loss of plasmid compared with inducible system,enhancing the plasmid stability of a constitutive system is more difficult.

• 与诱导型表达系统相比,在组成型表达系统中,由于外源蛋白的持续表达,导致细胞代谢负担加重,质粒稳定性的控制更加困难。