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Focal adhesion kinase (FAK) is the intermediator linking integrins to downstream signal proteins, and plays a key role in multiple signal pathways. 粘着斑激酶（focal adhesion kinase，FAK）则是整合素信号途径中连接整合素与下级信号分子的媒介，是胞内多条信号途径的交汇点。
OBJECTIVE ： To explore various signal pathways and their correlation in the proliferation and differentiation of Schwann cells. 目的：探讨许旺细胞增殖和分化过程中细胞内各种信号通路及其关联性。
The important signal pathways included mitosis pathways, growth factor pathways, developing pathways and mucin pathways. 如：有丝分裂信号通路、生长因子信号通路、与发育有关的信号通路和黏蛋白信号通路。
Many researches reveal that there are relations between cancers and aberrant activation or inactivation of signal pathways in cells. 现有研究揭示，许多癌症的发生与细胞内相关信号途径的异常激活或者失活相关。
The aim of the present study was to investigate the possible signal pathways involved in the cardiovascular regulation of adenosine in the NTS. 本研究的目的在于研究孤束核中腺苷参与心血管调节的可能存在的信号通路。
However, more research is necessary to do so.In this mini-review, we will focus on the potential signal pathways of BMPs in modulation the bone formation and regeneration. 在本篇回顾短文，我们将重点专注于骨形成蛋白参与骨形成过程所引发一连串的讯息作用途径，评估应用于骨或牙周组织再生之潜力。
Research indicated that PI3K and MAPK signal pathways were associated with biological behaviors such as cell migration, inflammation, cell proliferation and cell cycle regulation. 已有的研究表明PI3K和MAPK信号传导通路参与了细胞迁移、炎症反应、细胞增殖和细胞周期调控等一系列过程,在肾组织纤维化的发生发展中发挥重要作用。
Zhang -J et al.PDGF induces osteoprotegerin expression in vascular smooth muscle cells by multiple signal pathways[J]. FEBS-Lett.,2002 Jun 19;521(1-3):180-4. 廖二元等.;雌二醇对成骨细胞护骨素基因表达的影响[J]
On the other hand, CDPKs, belonged to a gene family with 34 isoforms in Arabdopsis and 27 in rice, have been found associated with multiple signal pathways, but function of each individual member still remains elusive. 作为一个基因家族,CDPKs在拟南芥中有34个成员,在水稻中有27个成员,研究证明它们与多种细胞信号传导有关,但每个成员的功能还不明确。
Methods We designed two novel peptides by simulating the partial active region of CTLA4 and CD40 molecules with bioinformatics technique and peptide synthesis in order to block these signal pathways. 方法我们运用生物信息学和多肽合成技术模拟CTLA4和CD40小分子肽 ,以阻断这些信号通路。
Myocyte apoptosis may play a pivotal role in MI,the suppression of Bcl-2 and the over expression of Bax,P53,Fas induce signal pathways of cardiomyocyte apoptosis, ACEI inhibits the cardiomyocyte apoptosis by effects of these genes. 大鼠急性心肌梗死后心肌细胞存在凋亡现象,Bcl-2表达下降,Bax、P53、Fas表达上调介导心肌梗死后心肌细胞凋亡的发生。 ACEI可通过干预上述基因抑制急性心肌梗死后的心肌细胞凋亡。
Such pathways in higher plants are similar, in part, to nodulation signal pathways in legumes and are related to calcium signaling. 高等植物中菌根形成的信号途径与豆科植物的结瘤信号途径部分共享, 并且与钙离子信号途径相关, 但前者更为广泛。
Activation and proliferation of HSC are regulated by several cytokines or signal regulatory proteins in vivo.The surface receptor can activate intracellular signal pathways with cytokines. 肝星状细胞在活化增殖过程中受多种细胞因子或蛋白的调控,通过表面受体激活信号转导网络系统,促使肝纤维化的发生发展。
Axon Guidance 1: Cues, Receptors, and Downstream Signalling Pathways Dickson, B. J. 轴突引导1:因子,接受器和下游信号传输。
Method: The expression of DDR and its downstream signaling pathways were detected by IHC, WB, RT-PCR and FQ-PCR. 方法:以瘢痕疙瘩组织和KFb为对象,应用IHC、FQ-PCR,WB、RT-PCR研究DDR在瘢痕疙瘩中的表达;
Signaling pathways downstream of pattern-recognition receptors and their cross talk. 信号通路下游的模式识别受体及其相互干扰作用。
The two-component system may also act as a module linking cytokinin and other signaling pathways. 细胞分裂素与其它信号途径的互作可能也主要是通过双元组分系统链接的。
In this review, we focus on JNK-mediated signaling pathways and the role of ROS in these pathways. 本文将主要总结JNK介导的信号转导途径及活性氧在这一途径中所发挥的作用。
In addition, substantial attentions have also been paid to crosstalks between cytokinin and other signaling pathways. 同时, 关于细胞分裂素与其它信号途径之间存在的广泛交叉反应也受到了人们的注意。
We also described the main signaling pathways that regulate the microfilament cytoskeleton. 本文还对调节微丝骨架的主要信号传递途径进行了综述。