Sheng di huang should not be used in cases of pixu with dampness, yangxu, and in pregnant women with blood deficiency of pixu or weixu (stomach deficiency).

• 生地黄?脾虚湿重?阳虚?大便溏泻者不宜用；中焦湿胜者要慎用为宜。怀孕期间有血虚?脾胃虚弱不宜用。