Several bacterial genes had been reported, including ompA, ibeA, ibeB , and yijP relating to invasion of BBB.The yijP gene also calledf577 and ibe23 , has a 1,734 - nucle-otide ORF.

• yijp基因，也称为f577或IBE23基因，其ORF为1734bp，推断的编码产物的分子量为66.；6KD，该蛋白参与大肠杆菌侵袭BMEC的机制不清。