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- Sandimmun Neoral 新山地明(微乳化环孢素)
- The relative bioavailability of CyA HP50 and CyA HP55 nanoparticles calculated by the AUC 0-72 were 82 3% and 119 6%, bioequivalent to the reference of Neoral. 与Neoral相比 ,CyA HP5 0NP与CyA HP5 5NP的相对生物利用度分别为 82 3%25和 1 1 9 6%25 ,均无显著性差异 ;
- METHODS :The study was conducted in 6 volunteers. After l single dose of domestic ciclosporine capsule or sandimmun capsule was taken,blood samples were taken and blood drug concentration was determined by FPLA method. 方法:对6例健康志愿者进行自身交叉口服单剂量田可及新山地明胶囊,用FPIA法测其全血浓度。
- Compared with the Neoral microemulsion,the relative bioavailability of CyA was 94.8%,115.2%,113.6% and 132.5% for CyA-E100,CyA-L100,CyA-L100-55 and CyA-S100 nanoparticles respectively. 与Neoral微乳相比; CyA E100;CyA L100;CyA L100 55和CyA S100纳米粒的相对生物利用度分别为94.;8%25;115
- CyA-S100 nanoparticles was shown to significantly improve the oral bioavailability of CyA compared with Neoral microemulsion ( P <0.05). While there were no significant differences between Neoral microemulsion and other CyA pH sensitive nanoparticles. 经统计分析;CyA S100纳米粒可以显著改善CyA的生物利用度(P<0.;05);而CyA L100 55纳米 粒;CyA L100纳米粒和CyA E100纳米粒与Neoral微乳相比无显著性差异。
- Neoral C2 monitoring in Chinese renal transplantation recipients 国人肾移植术后微乳化环孢素血药浓度C2监测的临床意义
- Analysis of variability of drug exposure and blood concentration during Neoral absorption phase in Chinese adult liver transplant recipients Neoral吸收期血药浓度和药物暴露量在中国成人肝移植受体中的变异性分析
- Sandimmun 山地明(环孢素制剂)
- Sandimmun(e) 山地明(环孢素制剂)
- Neoral Oral Solution 环孢菌素口服液
- neoral network (NN) S-B自适应频率采样技术
- Neoral 内奥拉尔