SU-DHL-9 had homozygous deletion of p16 gene. Meanwhile, SU-DHL-1 and Daudi cell lines had mutation of the second exon of p16 gene. GAC in codon 30 mutated into AAC.

• SU-DHL-9有p16基因的纯合缺失,而SU-DHL-1和Daudi细胞系有p16基因的第二外显子的突变,SU-DHL-1的测序结果为密码子30的GAC突变为AAC,密码子35的GCT突变为ACT,密码子40与41之间插入了一个C;