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- Rho kinase inhibitor Rho激酶抑制剂
- Rho kinase inhibitors Rho激酶抑制剂
- Is PDGF tyrosine kinase inhibitor effective in pancreatic cancer? PDGF受体酪氨酸激酶抑制剂在胰腺癌中是否有作用?
- Sunitinb is a novel multitargeted receptor tyrosine kinase inhibitor. 苏尼替尼是一种新型的多靶点酪氨酸激酶抑制剂。
- The progress in tyrosine kinase inhibitor has been reviewed, including the chemical structures and the pharmacophore models. 本文综述了近年来酪氨酸激酶抑制剂的研究进展，包括抑制剂的结构和与激酶作用的药效团模型。
- Volatile anesthetic agents such as halothane,isoflurane,sevoflurane have demon- strated to attenuate [Ca~(2+)] i and inhibit activation of PKC,Rho kinase and p44/42 MAPK of VSM. Volatile anesthetics also depress release of EDRFs and open K_(ATP)channel. 吸入性麻醉药如氟烷、异氟醚、七氟醚等被证明通过抑制平滑肌[Ca~(2+)]i升高和PKC、Rho激酶、p44/42 MAPK的活性、同时也通过抑制EDRFs的释放和增加K_(ATP)通道的开放来扩张血管。
- And PI3 kinase inhibitor LY294002 blocked the differentiation of ADAS cells into endothelial cells in vitro. 利用信号通路特异性抑制剂抑制实验，提示PI3K在ADAS细胞向内皮细胞分化中
- Gefitinib, the first EGFR tyrosine kinase inhibitor put into clinical trial, was put into market in Japan in 2002. 吉非替尼是EGFR酪氨酸激酶抑制剂中最早进入临床试验的口服药物，2002年首次于日本上市。
- EGFR tyrosine kinase inhibitor is an investigative hot spot in targeted therapy of non-small cell lung cancer (NSCLC). 摘要EGFR靶向抑制剂，是目前NSCLC靶向治疗的研究热点之一。
- Gefitinib (Iressa, ZD1839), a specific tyrosine kinase inhibitor that targets the epidermal growth factor receptor (EGFR), is a novel molecular-targeting antineoplastic agent. 摘要吉非替尼是一种新型的分子靶向抗癌药物，它选择性抑制表皮生长因子受体酪氨酸激酶而发挥作用。
- Objective To assess the effect of tyrosine kinase inhibitor (2,5-MC) on the inhibition of in-stent inti-mal hyperplasia. 目的评估酪氨酸蛋白激酶抑制剂2,5-MC抑制支架植入术后内膜增殖的效果。
- Expression of cyc lin-dependent kinase inhibitor p21waf/cip1 up-regulated after treated with MG1 32 for 3 h, but no p53 or p27 detected. 细胞周期检查点的负调控因子p21waf/cip1蛋白在加MG132处理后3h有明显的表达,但并未能检测到p53和p27蛋白。
- In the recent years, cyclin, cyc-lin dependent kinase and cyclin dependent kinase inhibitor have important effect in cell cycle modulation. 近年来发现细胞周期素(Cyclin)、细胞周期蛋白依赖激酶(Cyclin dependent kinase，CDK)和细胞周期蛋白依赖性激酶抑制因子(Cyclin dependent kinase inhibitor，CKI)在真核生物细胞周期调控有重要作用。
- P21WAF1 is a kind of cyclin dependent kinase inhibitor, it can be bind to several kinds of cyclin/CDK compounds and arrest the cell cycle. P21~(WAF1)是一种CKI，它可与多种cyclin/CDK复合物结合，引起细胞周期阻滞。
- Treatment of cells with the kinase inhibitor STI571 for 4-h reversed changes in expression of some of these cytoskeletal proteins. 当将这些细胞与激酶抑制剂STI571一起培养4小时后发现：细胞骨架蛋白的表达得到恢复。
- Rice cyclin-dependent kinase inhibitor(ICK)is a key control protein in cell-cycle, it can effect the growth and development of cell. 细胞周期蛋白依赖性激酶抑制剂(ICK)是一种能够影响细胞生长和发育的重要调控蛋白。
- Influences of ERK1/2 upstream kinase inhibitor U0126 as well as endothelium integrity on 15-HETE-induced HPV were observed. 用ERK1/2上游激酶抑制剂U0126孵育肺动脉环，比较U0126孵育前后15-HETE对缺氧性肺动脉环的收缩作用；
- Altenusin was reported as myosin light chain kinase inhibitor and sphingomyelinase inhibitor.TAN-420E has antitumor activity. TAN-420E曾报道有抗肿瘤活性，易氧化为Herbimycin A，后者是很好的除草剂，并具有一定抗菌活性。
- Abstract: Rice cyclin-dependent kinase inhibitor(ICK)is a key control protein in cell-cycle, it can effect the growth and development of cell. 摘要: 细胞周期蛋白依赖性激酶抑制剂(ICK)是一种能够影响细胞生长和发育的重要调控蛋白。
- P 27Klpl is a kind of cyclin dependnt kinase inhibitor (CKI) and it can regulate cell cycle through restraining cyclin and cyclin dependnt kinase (CDK). _p27蛋白是一种细胞周期蛋白依赖性激酶抑制剂(cyclin dependnt助兴大尝医笋朦硕生~研羌生.;早业讼戈
