Results: Compared with normal group, the normal hepatic lobules in model group were disappeared and fibroplasias formed nodus and false folial;hepatic cell become large, and ultrastructure damaged;

• 结果：与正常组相比，模型组大鼠肝小叶正常结构消失，肝间质广泛纤维组织增生，形成结节（假小叶），肝细胞体积明显增大，超微结构明显异常；