Results Contrast media significantly and selectively enhanced the arterial sensitivity to endothelin.This alteration was mediated by ETA receptor and was not influenced by osmolarity.

• 结果造影剂能够显著地、特异性地提高大鼠肾动脉对ET缩血管作用的敏感性，此作用主要由ETA受体介导，与渗透压无关；