Results Compared with reported method,two reaction stages (3,17-diacetylation and hydrolysis) were omitted in improved synthesis.The structure of obtained 2-methoxyestradiol was confirmed via 1H?

• 结果改进的合成方法割除了文献报道方法中的3,17双乙酰化及水解二个反应步骤,合成获得的2甲氧基雌二醇成品进行了结构确证。