Results Chiral docetaxel C13 side chain was synthesized in 76% yield and 99% ee.The total yield of coupling and deprotecting reaction was 64%.

• 结果多烯紫杉醇手性C13侧链的4步反应总收率为76%25，光学产率为99%25，对接及去保护3步反应总收率为64%25。