Recently, Robo4 (magic roundabout,MRB), a new member of Robo family, has been found, which is endothelial specific and expressed at sites of active angiogenesis, with the function of mediating the migration of endothelial cells.
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近期,人们研究发现Robo家族的一个新成员Robo4(又称magic roundabout,MRB)特异表达于血管生成活跃的内皮细胞表面,并参与调控内皮细胞迁移。
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