Rearrangements and mutations involving the RET(Rearranged During Transfection) proto-oncogene have been implicated closely in the papillary thyroid carcinoma(PTC).

• 原癌基因重排及突变与甲状腺乳头状癌(PTC)密切相关,它在调节细胞增殖、迁移、分化过程中具有重要意义。