Ratio of CD// CDg+ decreased, Thl/ Th2 cytokine lost balance. The two groups had distint differences. lt was indicated that the differences of immunity cloud provide objective basis for TCM differentiation of symptoms and signs.

• 肝郁脾虚型、湿热中阻型慢乙肝患者均存在明显的免疫功能紊乱，CD_4~+/CD_8~+降低，Th1/Th2细胞失衡，且两型之间差异明显，提示两证型免疫水平的差异可作为两证型中医辨证的客观化、量化指标，免疫辨证治疗慢性乙型肝炎成为可能。