Rat model with insulin resistance (IR) was induced by high fructose diet and the extent of IR was assayed by hyperinsulinemic euglycemic clamp technique.

• 本研究以高果糖饲料诱导胰岛素抵抗(IR)大鼠模型。高胰岛素正葡萄糖钳夹技术证实的胰岛素抵抗(IR)大鼠模型中增食欲素、瘦素的变化。