Ran GTPases, like other small GTPases, cycle between GDP-and GTP-bound states. However, for Ran GTPases, GTP binding and hydrolysis is linked to transport into or out of the nucleus .

• 同其他小G蛋白一样，也有GDP和GTP-结合态循环方式，而且这种循环方式还与核孔运输有关。