RG showed a tendency to promotethe sleep induced by sodium phenobarbital in normal mice, while markedly shortened the sleep in CCI4-treated mice.

• 龙胆对苯巴比妥钠所致正常小鼠的睡眠有协同作用，但对CCl4中毒小鼠则显著缩短苯巴比妥钠睡眠时间及延长翻正反射消失的时间。