RESULTS:Advance in second generation macrolides antibiotic has been swift in recent years,it has a broad antibacterial spectrum against gram-positive and gram-negative bacteria and anaerobes.

• 结果:第2代大环内酯抗生素研究进展迅速,其抗菌谱更趋广泛,对需氧菌和厌氧菌的抗菌能力较第1代的红霉素均有所增强。