Purpose: To prepare a poly-D-lysine-filled membrane which can well remove the unconjuated bilirubin, and to develop a mathematical model for facilitated transport in fixed site carriers membrane.

• 对常规聚砜膜的制备方法进行改进,制备了有利于载体固定的大孔聚砜膜,并将聚赖氨酸固定于聚砜膜中制得固定聚赖氨酸促进传递膜。