Prior infusion with UDCA (0.1 mmol/L) for 30 min followed by combination of UDCA and CDCA improved bile secretion, delayed enzyme release and partly prevented the membrane lesion caused by CDCA compared with CDCA alone.

• 预灌注 UDCA可部分缓解 CDCA引起的GL DH释放和胆汁分泌减少 ,稳定线粒体膜结构。