Preincubation of the cultures with ciliary neurotrophic factor (CNTF) for 24 h promoted neuronal survival and decreased the LDH efflux and the level of NO induced by ionomycin.

• 提前24 h给予不同浓度CNTF, 均能提高神经元的存活率, 减少LDH漏出, 其作用呈剂量依赖性;CNTF可降低ionomycin引起的NO含量升高;